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EMR1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 27044-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16805345

  • 112.71€ / 20µL

Expédition estimée
08-03-2021

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Description

Description

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.
Spécification

Spécification

EMR1
0.47 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q14246, Q61549
ADGRE1, Adhesion G protein-coupled receptor E1, EGF like module receptor 1, EMR1, EMR1 hormone receptor, F4/80, TM7LN3
Rabbit
IgG
20 μL
-20°C
Primary
13733, 2015
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
ADGRE1
Liquid
ADGRE1
EMR1 Fusion Protein Ag25883
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Vidéos
FDS
Documents