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ESX1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14657-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16803414

  • 112.71€ / 20µL

Expédition estimée
26-02-2021

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Description

Description

Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.
Spécification

Spécification

ESX1
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8N693
ESX homeobox 1, ESX1, ESX1L, ESX1R, ESXR1, Homeobox protein ESX1
Rabbit
IgG
20 μL
-20°C
Primary
13984, 80712
Western Blot, Immunoprecipitation
Unconjugated
ESX1
Liquid
ESX1
ESX1 Fusion Protein Ag6269
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Vidéos
FDS
Documents