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EWS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 55191-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16806685

  • 112.71€ / 20µL

Expédition estimée
03-03-2021

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Description

Description

This antibody is specific to EWS. A 90 kDa band also could be detected.

This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a ttranslocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
Spécification

Spécification

EWS
0.57 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q01844, Q61545
EWS, EWS oncogene, EWSR1, RNA binding protein EWS
Rabbit
IgG
20 μL
-20°C
Primary
14030, 2130, 289752
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
EWSR1
Liquid
Ewsr1
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Rat, Mouse
Vidéos
FDS
Documents