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FADD Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14906-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16803814

  • 112.71€ / 20µL

Expédition estimée
26-02-2021

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Description

Description

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Spécification

Spécification

FADD
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q13158, Q61160
FADD, GIG3, MORT1, Protein FADD
Rabbit
IgG
20 μL
-20°C
Primary
14082, 266610, 8772
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Immunofluorescence
Unconjugated
FADD
Liquid
FADD
FADD Fusion Protein Ag6701
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Vidéos
FDS
Documents