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GPR37/Pael-R Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 14820-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
This antibody recognizes endogenous GPR37, which migrates as an approximately 50-55 kDa band in SDS-PAGE.
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.Spécification
GPR37/Pael-R | |
Polyclonal | |
Unconjugated | |
GPR37 | |
EDNRBL, ETBR LP 1, GPR37, hET(B)R LP, PAELR, Pael-R | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
117549, 14763, 2861 | |
-20°C | |
Liquid |
Western Blot | |
0.31 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
O15354, Q9QY42, Q9QYC6 | |
GPR37 | |
GPR37/Pael-R Fusion Protein Ag6591 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |