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GPR37/Pael-R Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14820-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16833664

  • 399.00€ / 150µL
Expédition estimée: 12-04-2024
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Description

Description

This antibody recognizes endogenous GPR37, which migrates as an approximately 50-55 kDa band in SDS-PAGE.

Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
Spécification

Spécification

GPR37/Pael-R
Polyclonal
Unconjugated
GPR37
EDNRBL, ETBR LP 1, GPR37, hET(B)R LP, PAELR, Pael-R
Rabbit
Antigen Affinity Chromatography
RUO
117549, 14763, 2861
-20°C
Liquid
Western Blot
0.31 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O15354, Q9QY42, Q9QYC6
GPR37
GPR37/Pael-R Fusion Protein Ag6591
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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