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GTF2H1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 10173-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16806383

  • 112.71€ / 20µL

Expédition estimée
09-03-2021

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Description

Description

TFIIH, a multisubunit complex is involved in several biological fundamental mechanisms of the cell: transcription, nucleotide excision repair and cell cycle regulation. p62 is one of the six subunits that constitutes the core of TFIIH. Analysis of the expression of the p62 gene reveals an over expression in testis tissue. This subunit of TFIIH participates in a variety of protein interactions. For example, Rb competes with TBP and p62 for binding to E2F thus repressing E2F mediated transactivation; herpes simplex virus VP16 and human p53, directly interact with the p62 subunit of TFIIH. In addition, TFIIH, via p62 phosphorylation is the major target for mitotic inactivation of transcription. GTF2H1 is a component of the core GTF2H basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. GTF2H1 is one of the six subunits forming the core GTF2H basal transcription factor.
Spécification

Spécification

GTF2H1
0.5 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P32780, Q9DBA9
BTF2, BTF2 p62, GTF2H1, TFB1, TFIIH
Rabbit
IgG
20 μL
-20°C
Primary
14884, 2965
Western Blot
Unconjugated
GTF2H1
Liquid
Gtf2h1
GTF2H1 Fusion Protein Ag0229
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Mouse, Human
Vidéos
FDS
Documents