missing translation for 'onlineSavingsMsg'
Learn More
Learn More
GTF2H1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 10173-1-AP-20UL
Informations supplémentaires : Poids : 0.00010kg
Description
TFIIH, a multisubunit complex is involved in several biological fundamental mechanisms of the cell: transcription, nucleotide excision repair and cell cycle regulation. p62 is one of the six subunits that constitutes the core of TFIIH. Analysis of the expression of the p62 gene reveals an over expression in testis tissue. This subunit of TFIIH participates in a variety of protein interactions. For example, Rb competes with TBP and p62 for binding to E2F thus repressing E2F mediated transactivation; herpes simplex virus VP16 and human p53, directly interact with the p62 subunit of TFIIH. In addition, TFIIH, via p62 phosphorylation is the major target for mitotic inactivation of transcription. GTF2H1 is a component of the core GTF2H basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. GTF2H1 is one of the six subunits forming the core GTF2H basal transcription factor.Spécification
GTF2H1 | |
Polyclonal | |
Unconjugated | |
GTF2H1 | |
BTF2, BTF2 p62, GTF2H1, TFB1, TFIIH | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
14884, 2965 | |
-20°C | |
Liquid |
Western Blot | |
0.5 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P32780, Q9DBA9 | |
Gtf2h1 | |
GTF2H1 Fusion Protein Ag0229 | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |