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hnRNP-E1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14523-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16803204

  • 399.00€ / 150µL
Expédition estimée: 12-04-2024
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Description

Description

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular polydomains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5′-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.
Spécification

Spécification

hnRNP-E1
Polyclonal
Unconjugated
PCBP1
Alpha CP1, hnRNP E1, hnRNP X, HNRPE1, HNRPX, PCBP1, poly(rC) binding protein 1
Rabbit
Antigen Affinity Chromatography
RUO
23983, 500242, 5093
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P60335, Q15365
PCBP1
hnRNP-E1 Fusion Protein Ag6007
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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