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ACROBiosystems Human APRIL / TNFSF13 Protein, Mouse IgG2a Fc Tag

Marque:  ACROBiosystems APL-H5256-100ug

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 17266050

  • 399.17€ / 100µg
Expédition estimée: 05-01-2023
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Description

Description

APRIL(a proliferation-inducing ligand) is also known as Tumor necrosis factor ligand superfamily member 13, TALL-2, TRDL-1, CD256, TNFFSF 13, cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. APRIL is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. The closely related TNF family ligands B cell activation factor (BAFF) and a proliferation-inducing ligand (APRIL) serve in the generation and maintenance of mature B-lymphocytes. Both BAFF and APRIL assemble as homotrimers that bind and activate several receptors that they partially share. BAFF-APRIL heteromers of different stoichiometries have distinct receptor-binding properties and activities. In addition, expression of APRIL was regulated by miR-145 in GC cells.

This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 43.2 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_003799.1
43.2 kDa
Human APRIL, Mouse IgG2a Fc Tag (APL-H5256) is expressed from human 293 cells (HEK293). It contains AA Ala 105 - Leu 250 (Accession # O75888-1).
-20°C
APRIL
Mouse IgG Fc Tag
Less than 0.1 EU / μg by the LAL method.
Bio-Markers & CD Antigens
Powder
100 μg
Ala 105 - Leu 250
APRIL,TNFSF13,TALL-2,TRDL-1,CD256,TALL2,ZTNF2
Unconjugated
PBS, pH7.4
HEK293
Human
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