missing translation for 'onlineSavingsMsg'
Learn More
Learn More
ACROBiosystems Human CD38 Protein, Llama IgG2b Fc Tag, low endotoxin
low endotoxin
Marque: ACROBiosystems CD8-H5252-1MG
Informations supplémentaires : Poids : 0.00001kg
Description
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 57.7 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
| NP_001766.2 | |
| 1 mg | |
| Val 43 - Ile 300 | |
| CD38,T10,cADPr hydrolase 1 | |
| Unconjugated | |
| Llama IgG Fc Tag | |
| Less than 0.01 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 57.7 kDa | |
| Human CD38, Llama IgG2b Fc Tag, low endotoxin (CD8-H5252) is expressed from human 293 cells (HEK293). It contains AA Val 43 - Ile 300 (Accession # P28907-1). | |
| -20°C | |
| CD38 | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| Bio-Markers and CD Antigens |