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ACROBiosystems Human CEACAM-8 / CD66b Protein, His Tag
Marque: ACROBiosystems CE8-H5224-1MG
Informations supplémentaires : Poids : 0.00001kg
Description
Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA-95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is an activation marker for human granulocytes.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.2 kDa. The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
| NP_001807.2 | |
| 1 mg | |
| Gln 35 - Ser 319 | |
| CEACAM8,CD66b,CD67,CGM6,NCA-95 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 32.2 kDa | |
| Human CEACAM-8, His Tag (CE8-H5224) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Ser 319 (Accession # NP_001807.2). | |
| -20°C | |
| CEACAM-8 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |