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ACROBiosystems Human DPPIV / CD26 Protein, His Tag (Active dimer) (active enzyme)
447.57€ - 919.33€
Spécification
Numéro d’adhésion | NP_001926.2 |
---|---|
Poids moléculaire | 85.7 kDa |
Source | Human DPPIV, His Tag (DP4-H5221) is expressed from human 293 cells (HEK293). It contains AA Asp 34 - Pro 766 (Accession # NP_001926.2). |
Immunogène | Asp 34 - Pro 766 |
Conditions de stockage | -20°C |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15886587
|
ACROBiosystems
DP4-H5221-50UG |
50 μg |
447.57€
50µg |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
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15876587
|
ACROBiosystems
DP4-H5221-200UG |
200 μg |
919.33€
200µg |
Expédition estimée: 03-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Dipeptidyl peptidase-IV (DPPIV) is also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 85.7 kDa. The protein migrates as 95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
NP_001926.2 | |
Human DPPIV, His Tag (DP4-H5221) is expressed from human 293 cells (HEK293). It contains AA Asp 34 - Pro 766 (Accession # NP_001926.2). | |
-20°C | |
DPPIV | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Enzymes |
85.7 kDa | |
Asp 34 - Pro 766 | |
DPP4,ADABP,ADCP2,CD26,DPPIV,TP103 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |