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ACROBiosystems Human Frizzled-4 / FZD4 Protein, Fc Tag

Marque:  ACROBiosystems FZ4-H5250-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15866797

  • 1614.07€ / 1mg
Date d’expédition estimée: 28-12-2021

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Description

Description

Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.9 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

AAI14528
HEK293
Human
42.9 kDa
1 mg
Phe 37 - Glu 180
FZD4,Frizzled-4,CD344,Fz-4,hFz4,FzE4
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human Frizzled-4, Fc Tag (FZ4-H5250) is expressed from human 293 cells (HEK293). It contains AA Phe 37 - Glu 180 (Accession # AAI14528).
-20°C
Frizzled-4
Fc Tag
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