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ACROBiosystems Human Frizzled-5 / FZD5 Protein, Fc Tag

Marque:  ACROBiosystems FZ5-H5259-100UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15876797

  • 262.28€ / 100µg
Date d’expédition estimée: 10-01-2022

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Description

Description

Frizzled-5 (FZD5) is also known as FzE5, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the beta-catenin pathway. FZD5 interacts with GOPC.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.6 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

Q13467
HEK293
Human
42.6 kDa
100 µg
Ala 27 - Pro 167
FZD5,Frizzled-5,C2orf31,,Fz-5,hFz5,FzE5
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human Frizzled-5, Fc Tag (FZ5-H5259) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Pro 167 (Accession # Q13467).
-20°C
Frizzled-5
Fc Tag
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