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ACROBiosystems Human GITR / TNFRSF18 Protein, Mouse IgG2a Fc Tag, low endotoxin

low endotoxin

Marque:  ACROBiosystems GIR-H525A-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15866847

  • 1997.41€ / 1mg
Date d’expédition estimée: 05-01-2022

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Description

Description

Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 41.4 kDa. The protein migrates as 46-49 kDa and 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_004186.1
HEK293
Human
41.4 kDa
1 mg
Gln 26 - Glu 161
AITR,GITR,TNFRSF18,CD357
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 0.1 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Human GITR, Mouse IgG2a Fc Tag, low endotoxin (GIR-H525a) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # Q9Y5U5-1).
-20°C
GITR
Mouse IgG Fc Tag
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