missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Human Her2 / ErbB2 Protein, His Tag

MALS verified

443.87€ - 3191.09€

Spécification

Numéro d’adhésion NP_004439.2
Poids moléculaire 70.2 kDa
Source Human Her2, His Tag (HE2-H5225) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 (Accession # P04626-1).
Immunogène Thr 23 - Thr 652
Conditions de stockage -20°C
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
15846927
Afficher les documents Détails de la promotion
ACROBiosystems
HE2-H5225-100UG
100 μg
443.87€
100µg
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 10-04-2024
pour voir le stock disponible 
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
15856927
Afficher les documents Détails de la promotion
ACROBiosystems
HE2-H5225-1MG
1 mg
3191.09€
1mg
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée: 10-04-2024
pour voir le stock disponible 
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
Description

Description

Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 70.2 kDa. The protein migrates as 110-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_004439.2
Human Her2, His Tag (HE2-H5225) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 (Accession # P04626-1).
-20°C
Her2
Human
PBS, pH7.4
HEK293
Bio-Markers and CD Antigens
70.2 kDa
Thr 23 - Thr 652
ERBB2,CD340,HER-2/neu,HER2,MLN19,NEU,NGL,TKR1
Unconjugated
His Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
Vidéos
FDS
Documents

Documents

Product Certifications