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ACROBiosystems Human IL-2 R beta / CD122 Protein, Fc Tag

SPR verified

Marque:  ACROBiosystems ILB-H5253-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867087

  • 2622.86€ / 1mg
Date d’expédition estimée: 05-01-2022

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Description

Description

Interleukin-2 receptor subunit beta (IL2RB) is also known as CD122, which Belongs to the type I cytokine receptor family. Type 4 subfamily. IL2RB contains 1 fibronectin type-III domain. IL2RB / CD122 is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. The protein migrates as 62-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_000869.1
HEK293
Human
50.7 kDa
1 mg
Ala 27 - Asp 239
IL2RB,RP5-1170K4.6,CD122,P70-75
Unconjugated
50 mM Tris, 100 mM Glycine, pH7.5
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human IL-2 R beta, Fc Tag (SPR verified) (ILB-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Asp 239 (Accession # NP_000869.1).
-20°C
IL-2 R beta
Fc Tag
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