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Gibco™ Human IL-36 beta (IL-1F8) Recombinant Protein, PeproTech®
E. coli Recombinant Protein
Marque: Gibco™ 200-36B-2UG
Informations supplémentaires : Poids : 0.16500kg
Description
IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP. Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown. The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.Spécification
| Q9NZH7 | |
| protein with no preservative | |
| 17.3 | |
| 2 µg | |
| -20°C | |
| <1 EU/µg | |
| IL36B | |
| Unconjugated | |
| MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 27177 | |
| Human IL-36 beta (IL-1F8) | |
| E. coli | |
| RUO | |
| 2310043N20Rik; family of interleukin 1-eta; FIL1; FIL1 eta; FIL1-(ETA); Fil1e; FIL1H; FILI-(ETA); IL-1 eta; IL1-ETA; IL1F8; IL-1F8; IL1F8 (Canonical product IL-1F8a); IL-1F8 (FIL1-eta); IL1H2; IL-1H2; Il36b; interleukin 1 family, member 8; interleukin 1 family, member 8 (eta); interleukin 1, eta; interleukin 36, beta; interleukin-1 eta; Interleukin-1 family member 8; interleukin-1 homolog 2; Interleukin-1 Superfamily e; interleukin-36 beta | |
| Human | |
| Recombinant | |
| Lyophilized |