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ACROBiosystems Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein, His Tag&Tag Free
Marque: ACROBiosystems IT3-H52E3-100UG
Informations supplémentaires : Poids : 0.00001kg
Description
Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Also, Integrin alpha-V/beta-3 acts as a receptor for herpes virus 8/HHV-8, coxsackievirus A9, Hantaan virus, cytomegalovirus/HHV-5, human metapneumovirus, human parechovirus 1 and west nile virus. Furthermore, in case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Human ITGAV&ITGB3 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGAV and ITGB3, has a calculated MW of 112.9 kDa (ITGAV) and 81.8 kDa (ITGB3). Subunit ITGAV is fused with an acidic tail at the C-terminus and followed by a polyhistidSpécification
NP_002201.1 (ITGAV) and NP_000203.2 (ITGB3) | |
100 μg | |
Phe 31 - Val 992 (ITGAV) and Gly 27 - Asp 718 (ITGB3) | |
Integrin alpha V beta 3,ITGAVandITGB3 | |
Unconjugated | |
His Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
112.9 kDa (ITGAV) and 81.8 kDa (ITGB3) | |
Human ITGAV&ITGB3; Heterodimer Protein, His Tag&Tag; Free (IT3-H52E3) is expressed from human 293 cells (HEK293). It contains AA Phe 31 - Val 992 (ITGAV) and Gly 27 - Asp 718 (ITGB3) (Accession # NP_002201.1 (ITGAV) and NP_000203.2 (ITGB3)). | |
-20°C | |
Integrin alpha V beta 3 | |
Human | |
50 mM Tris, 150 mM NaCl, pH7.5 | |
HEK293 | |
Bio-Markers and CD Antigens |