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ACROBiosystems Human LILRB3 / CD85a / ILT5 Protein, Fc Tag

Marque:  ACROBiosystems CDA-H5250-100UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15866337

  • 317.77€ / 100µg
Date d’expédition estimée: 07-01-2022

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Description

Description

Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.8 kDa. As a result of glycosylation, the protein migrates as 90-115 kDa under reducing (R) condition, and 150 kDa under non-reducing (NR) condition (SDS-PAGE
Spécification

Spécification

AAB68668 (P288R)
HEK293
Human
72.8 kDa
100 µg
Gly 24 - Glu 443
LILRB3,CD85a,ILT5
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Human LILRB3, Fc Tag (CDA-H5250) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 443 (Accession # AAB68668 (P288R)).
-20°C
LILRB3
Fc Tag
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