ACROBiosystems Human LY75 / CD205 Protein, His Tag
Marque: ACROBiosystems LY5-H52H3-1mg
Informations supplémentaires : Poids : 0.00010kg
lymphocyte antigen 75 (Ly 75, also known as CD205, CLEC13B, GP200-MR6 and DEC-205, is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. LY75 functions as an endocytic receptor for antigens. MEN1309/OBT076, the first antibody drug targeting CD205, has shown strong preclinical anti-tumor activity in lymphoma. After being verified as a single drug in vivo, the antibody-drug conjugate has a synergistic effect with the BCL2 inhibitor Venetoclax and the anti-cd20 monoclonal antibody rituximab.This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 190.7 kDa.
|Ser 28 - Asp 1666|
|LY75,CD205,DEC-205,CLEC13B,Lymphocyte antigen 75,gp200-MR6|
|Human LY75, His Tag (LY5-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 28 - Asp 1666 (Accession # O60449-1).|
|Bio-Markers & CD Antigens|