missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Human OX40 Ligand / TNFSF4 Protein, Fc Tag

Marque:  ACROBiosystems OXL-H526X-1MG

Informations supplémentaires : Poids : 0.00001kg

 Afficher plus de versions de ce produit

Code produit. 15877417

  • 1997.41€ / 1mg
Date d’expédition estimée: 05-01-2022

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.

This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 42.4 kDa. The protein migrates as 53-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_003317
HEK293
Human
42.4 kDa
1 mg
Gln 51 - Leu 183
OX40L,TNFSF4,CD252,Glycoprotein Gp34,TXGP1,CD134 ligand,CD134L
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>90% as determined by SDS-PAGE
Human O x 40 Ligand, Fc Tag (OXL-H526x) is expressed from human 293 cells (HEK293). It contains AA Gln 51 - Leu 183 (Accession # NP_003317).
-20°C
OX40 Ligand
Fc Tag
Vidéos
FDS
Documents
Certificats
Promotions

Promotions