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ACROBiosystems Human PD-L2 / B7-DC Protein, Fc Tag

HPLC-verified

Marque:  ACROBiosystems PD2-H5251-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867507

  • 2267.35€ / 1mg
Expédition estimée: 11-04-2024
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Description

Description

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.2 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

AAI13679
1 mg
Leu 20 - Pro 219
PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2
Unconjugated
Fc Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
49.2 kDa
Human PD-L2, Fc Tag (HPLC verified) (PD2-H5251) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # AAI13679).
-20°C
PD-L2
Human
PBS, pH7.4
HEK293
Immune Checkpoint Proteins
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