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ACROBiosystems Human ROR1 (165-305, Frizzled domain) Protein, His Tag
495.95€ - 3762.02€
Spécification
| Numéro d’adhésion | Q01973 |
|---|---|
| Poids moléculaire | 16.7 kDa |
| Source | Human ROR1 (165-305, Frizzled domain), His Tag (RO1-H5222) is expressed from human 293 cells (HEK293). It contains AA Glu 165 - Asp 305 (Accession # Q01973-1). |
| Immunogène | Glu 165 - Asp 305 |
| Conditions de stockage | -20°C |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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15857587
|
ACROBiosystems
RO1-H5222-1MG |
1 mg |
3762.02€
1mg |
Expédition estimée: 02-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
|
15867587
|
ACROBiosystems
RO1-H5222-50UG |
50 μg |
495.95€
50µg |
Expédition estimée: 02-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1ε) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.7 kDa. The protein migrates as 19-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spécification
| Q01973 | |
| Human ROR1 (165-305, Frizzled domain), His Tag (RO1-H5222) is expressed from human 293 cells (HEK293). It contains AA Glu 165 - Asp 305 (Accession # Q01973-1). | |
| -20°C | |
| ROR1 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 16.7 kDa | |
| Glu 165 - Asp 305 | |
| ROR1,NTRKR1 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |