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ACROBiosystems Human SCARB1 / SR-B1 Protein, Fc Tag

Marque:  ACROBiosystems SC1-H5258-50UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867647

  • 317.77€ / 50µg
Date d’expédition estimée: 28-12-2021

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Description

Description

Scavenger receptor class B member 1 (SRB1) is also known as SR-BI, CD36 and LIMPII analogous 1 (CD36L1), CLA-1, is a member of the scavenger receptor family or CD36 family. CD36L1 is an integral membrane protein found in numerous cell types/tissues, including the liver and adrenal. SRB1 is receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. CLA-1 facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high-density lipoprotein (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. SCARB1 is, along with CD81, the receptor for the entry of the Hepatitis C virus glycoprotein E2 in liver cells, and binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. SRB1 plays an important role in the uptake of HDL cholesteryl ester.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 72.7 kDa. As a result of glycosylation, the protein migrates as 110-115 kDa under reducing (R) condition, and 220-230 kDa under non-reducing (NR) condition (SDS
Spécification

Spécification

NP_005496.4
HEK293
Human
72.7 kDa
50 µg
Pro 33 - Tyr 443
SCARB1,CD36L1,SRB1,CLA-1,SR-BI,HDLQTL6
Unconjugated
50 mM Tris, 100 mM Glycine, pH7.5
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Human SCARB1, Fc Tag (SC1-H5258) is expressed from human 293 cells (HEK293). It contains AA Pro 33 - Tyr 443 (Accession # NP_005496.4).
-20°C
SCARB1
Fc Tag
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