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ACROBiosystems Human TACI/TNFRSF13B Protein, Fc Tag

Marque:  ACROBiosystems TAI-H5256-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867737

  • 1926.79€ / 1mg
Date d’expédition estimée: 07-01-2022

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Description

Description

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.6 kDa. The protein migrates as 33-34 kDa, 35 kDa and 50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>90% as determined by reduced SDS-PAGE
Human TACI/TNFRSF13B, Fc Tag (TAI-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Thr 166 (Accession # O14836-1).
-20°C
TACI
Fc Tag
HEK293
Human
44.6 kDa
1 mg
Ser 2 - Thr 166
CD267,TACI,TNFRSF13B
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
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