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ACROBiosystems Human UCH-L1 Protein, His Tag

Marque:  ACROBiosystems UC1-H5140-50UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867887

  • 252.20€ / 50µg
Date d’expédition estimée: 10-01-2022

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Description

Description

Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL1) ,a member of the peptidase C12 family, is also known as neuron cytoplasmic protein 9.5 (PGP 9.5) and ubiquitin thioesterase L1.About 30% of total UCHL1 is associated with membranes in brain. UCHL1 is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also,UCHL1 can bind to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer of UCHL1 may have ATP-independent ubiquitin ligase activity. Furthermore, the mutations of UCHL1 gene can result in parkinson disease 5.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.7 kDa. The protein migrates as 27-28 kDa under reducing (R) condition (SDS-PAGE).
Spécification

Spécification

NP_004172
E.coli
Human
25.7 kDa
50 µg
Gln 2 - Ala 223
UCHL1,PGP9.5
Unconjugated
50 mM Tris, 150 mM Nacl, pH8.0
Less than 1.0 EU / µg by the LAL method.
Other Recombinant Proteins
Powder
>95% as determined by SDS-PAGE
Human UCH-L1, His Tag (UC1-H5140) is expressed from E.coli cells. It contains AA Gln 2 - Ala 223 (Accession # NP_004172).
-20°C
UCH-L1
His Tag
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