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ACROBiosystems Human VCAM-1 / CD106 Protein, His Tag

Marque:  ACROBiosystems VC1-H5224-1MG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15867897

  • 1513.19€ / 1mg
Date d’expédition estimée: 03-01-2022

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Description

Description

Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 74.9 kDa. The protein migrates as 80-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_001069
HEK293
Human
74.9 kDa
1 mg
Phe 25 - Pro 697
VCAM1,CD106,INCAM-100,V-CAM 1,VCAM-1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>92% as determined by SDS-PAGE
Human VCAM-1, His Tag (VC1-H5224) is expressed from human 293 cells (HEK293). It contains AA Phe 25 - Pro 697 (Accession # NP_001069).
-20°C
VCAM-1
His Tag
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