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ACROBiosystems Human ZNRF3 protein, His Tag (MALS verified)

Marque:  ACROBiosystems ZN3-H52H3-100ug

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 17256600

  • 399.17€ / 100µg
Expédition estimée: 17-10-2022
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Description

Description

The transmembrane E3 ubiquitin ligase zinc and ring finger 3 (ZNRF3) is a negative feedback regulator of Wnt signalling. ZNRF3 is associated with the Wnt receptor complex, and inhibits Wnt signalling by promoting the turnover of frizzled and LRP6 and acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.7 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_001193927.1
>95% as determined by SDS-PAGE.
Human ZNRF3, His Tag (ZN3-H52H3) is expressed from human 293 cells (HEK293). It contains AA Lys 56 - Met 219 (Accession # Q9ULT6-1).
-20°C
ZNRF3
His Tag
Less than 1.0 EU / µg by the LAL method.
Powder
Human
19.7 kDa
100 µg
Lys 56 - Met 219
ZNRF3, Zinc/RING finger protein 3, RING-type E3 ubiquitin transferase ZNRF3, RING finger protein 203, KIAA1133, RNF203
Unconjugated
PBS, pH7.4
HEK293
Other Recombinant Proteins
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