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IL-23 p19 Monoclonal Antibody (fc23cpg), eFluor™ 660, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
177.00€ - 401.00€
Spécification
Antigène | IL-23 p19 |
---|---|
Clone | fc23cpg |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
15341940
|
Affymetrix eBioscience
50-7023-80 |
25 μg |
177.00€
25µg |
Expédition estimée: 31-05-2024 Connectez-vous pour voir le stock disponible |
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15351940
|
Affymetrix eBioscience
50-7023-82 |
100 μg |
401.00€
100µg |
Expédition estimée: 07-05-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Description: This fc23cpg monoclonal antibody reacts with the p19 subunit of mouse IL-23, a heterodimeric cytokine made up of two disulfide-linked subunits, p40 and p19. It is closely related to IL-12, with which it shares the p40 subunit. IL-23 signals through a heterodimeric receptor expressed on activated T cells, macrophages, and dendritic cells. The receptor shares the IL-12Rbeta1 chain with IL-12, while the IL-23R chain is unique to the IL-23 receptor complex. Binding of IL-23 to its receptor activates Jak/STAT pathways similarly to IL-12, but the two cytokines exhibit distinct functions. Unlike IL-12, which induces T-bet and Th1 differentiation, IL-23 signaling results in RORgammat expression and supports CD4^+ T cells with the Th17 phenotype Dendritic cells and macrophages produce IL-23 in response to TLR2, TLR4, and TLR8 ligands, as well as agonists of the beta-glucan receptor, Dectin-1. Our studies suggest donor, kinetics and type of stimulant can result in variation in IL-23 expression levels. Recent publications suggest the p19 subunit may also exist in the absence of association with p40. Applications Reported: This fc23cpg antibody has been reported for use by intracellular staining and flow cytometric analysis. Applications Tested: This fc23cpg antibody has been tested by intracellular staining and flow cytometric analysis. This can be used at less than or equal to 0.06 μg per test.
IL-23 p19 Monoclonal antibody specifically detects IL-23 p19 in Mouse samples. It is validated for Flow Cytometry.Spécification
IL-23 p19 | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
il 23; IL 23 A; IL12B; Il-12b; Il12p40; Il-12p40; il23; IL-23; IL-23 subunit alpha; IL23A; IL-23A; IL-23-A; IL23P19; IL-23p19; ILN; Interleukin; interleukin 12B; interleukin 23 p19 subunit; interleukin 23 subunit alpha; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; interleukin-six, G-CSF related factor; JKA3 induced upon T-cell activation; MGC79388; P19; p40; RP23-388G23.1; SGRF; UNQ2498/PRO5798 | |
IL23A | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
fc23cpg | |
Flow Cytometry | |
eFluor 660 | |
Rat | |
Mouse | |
Q9EQ14 | |
83430 | |
mouse IL-23p19 subunit | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
IL23A |
For Research Use Only.