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KIR2DL4 Monoclonal Antibody (mAb#33), Invitrogen™

Mouse Monoclonal Antibody

Marque:  Invitrogen MA110143

Code produit. 12392163

  • 381.00€ / 100 pièces

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Description

Description

This antibody recognizes the extracellular portion of CD158d.

CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
TRUSTED_SUSTAINABILITY
Spécification

Spécification

KIR2DL4
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
Q99706
KIR2DL4
NK3.3 cells and KIR2DL4-Ig fusion protein
100 μg
Primary
Human
Antibody
IgG1 κ
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
mAb#33
Unconjugated
KIR2DL4
CD158 antigen-like family member D; CD158D; G9P; killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4; killer cell immunoglobulin-like receptor 2DL4; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4; killer cell inhibitory receptor 103AS; killer Ig receptor; killer-cell immunoglobulin-like receptor; killer-cell immunoglobulin-like receptor 2DL4; KIR; KIR103; KIR103AS; KIR-103AS; KIR2DL4; KIR-2DL4; MHC class I NK cell receptor KIR103AS; natural killer cell inhibitory receptor; natural killer cell receptor; NK cell receptor
Mouse
Protein A
RUO
3805
4° C, do not freeze
Liquid
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