KLRG1 Syrian Hamster anti-Mouse, eFluor® 450, Clone: 2F1, eBioscience™
Syrian Hamster Monoclonal Antibody
Marque: Affymetrix eBioscience 48-5893-82
Code nomenclature Nacres: NA.41
Informations supplémentaires : Poids : 0.25000kg
DescriptionCell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser. Filtration: 0.2 μm post-manufacturing filtered. KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, C-type lectin domain family 15 member A, C-type lectin domain family 15, member A, ITIM-containing receptor MAFA-L, MAFA-like receptor, killer cell lectin-like receptor subfamily G member 1, mast cell function-associated antigen (ITIM-containing)|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.