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Thermo Scientific™ LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit
LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit
Marque: Thermo Scientific™ PV4813
Code nomenclature Nacres: NA.41
Informations supplémentaires : Poids : 0.50000kg
Description
A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate inhibitors in medium to high throughput screening applications.Spécification
| Kinase Assay, Enzyme and Protein Activity Assays, Kinase Assay | |
| COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, CRAF,NS5,Raf-1,c-Ra, MEKK9,MLK1,PRKE, COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, MEKK7,TAK1,TGF1, MEKK9,MLK1,PRKE, ASK1,MAPKKK5,MEKK, MEKK10,MLK2,MS, MEKK11,MGC17114,MLK-3,MLK3,PTK1,SPR, CRAF,NS5,Raf-1,c-Ra, | |
| 25 μg | |
| Target and Lead Identification and Validation | |
| 10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885 | |
| 0.02% Sodium azide | |
| 150000 Da | |
| 384-well Plate | |
| Human | |
| End Point | |
| MAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3 | |
| TR-FRET |
| Tb (Terbium)/FITC/Lanthanide Chelates | |
| 150kDa | |
| RUO, RUO | |
| Primary | |
| 1 Kit(s) | |
| Terbium-labeled anti-MAP2K1 [pSer217/221] antibody in HEPES buffered saline. Store at -20°C. | |
| Biochemical terbium phospho-specific activity | |
| 340⁄490, 520 | |
| Dry Ice | |
| Hu | |
| Serine⁄Threonine Kinases | |
| BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11 |
For Research Use Only. Not for use in diagnostic procedures.