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MFN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 13798-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16832194

  • 121.38€ / 20µL
Expédition estimée: 03-10-2022
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Description

Description

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.
Spécification

Spécification

MFN1
Polyclonal
Unconjugated
MFN1
Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1
Rabbit
Antigen Affinity Chromatography
RUO
192647, 55669, 67414
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q811U4, Q8IWA4, Q8R4Z9
MFN1
MFN1 Fusion Protein Ag4762
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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