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MLH3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 25298-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16833885

  • 399.00€ / 150µL
Expédition estimée: 12-04-2024
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Description

Description

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Spécification

Spécification

MLH3
Polyclonal
Unconjugated
MLH3
HNPCC7, MLH3, mutL homolog 3 (E. coli), MutL protein homolog 3
Rabbit
Antigen Affinity Chromatography
RUO
27030
-20°C
Liquid
Western Blot
0.35 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q9UHC1
MLH3
MLH3 Fusion Protein Ag18201
150 μL
Primary
Human
Antibody
IgG
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