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ACROBiosystems Mouse CD27 Ligand / CD70 Protein, Mouse IgG2a Fc Tag, low endotoxin

low endotoxin

Marque:  ACROBiosystems CDL-M5251-100UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15866427

  • 302.64€ / 100µg
Date d’expédition estimée: 07-01-2022

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Description

Description

Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.

This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 43.5 kDa. The protein migrates as 47-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_035747.1
HEK293
Mouse
43.5 kDa
100 µg
Gln 47 - Pro 195
CD70,CD27LG,TNFSF7,TNFSF7G,CD27L
Unconjugated
50 mM Tris, 100 mM Glycine, pH7.5
Less than 0.1 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Mouse CD27 Ligand, Mouse IgG2a Fc Tag, low endotoxin (CDL-M5251) is expressed from human 293 cells (HEK293). It contains AA Gln 47 - Pro 195 (Accession # O55237-1).
-20°C
CD27 Ligand
Mouse IgG Fc Tag
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