missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Mouse Her2 / ErbB2 Protein, His Tag

Marque:  ACROBiosystems ER2-M5220-1MG

Informations supplémentaires : Poids : 0.00001kg

 Afficher plus de versions de ce produit

Code produit. 15866677

  • 2118.47€ / 1mg
Date d’expédition estimée: 28-12-2021

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 70.6 kDa. The protein migrates as 80-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

AAH53078.1
HEK293
Mouse
70.6 kDa
1 mg
Thr 23 - Thr 653
ERBB2,CD340,HER-2/neu,HER2,MLN19,NEU,NGL,TKR1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Mouse Her2, His Tag (ER2-M5220) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 653 (Accession # AAH53078.1).
-20°C
Her2
His Tag
Vidéos
FDS
Documents
Certificats
Promotions

Promotions