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ACROBiosystems Mouse IgG2a Fc Protein, Tag Free
Marque: ACROBiosystems IGA-M5207-1MG
Informations supplémentaires : Poids : 0.00001kg
Description
Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
This protein carries no "e;tag"e;. The protein has a calculated MW of 26.4 kDa. As a result of glycosylation, the protein migrates as 30-35 kDa under reducing (R) condition, and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE).Spécification
| CAC20702 | |
| 1 mg | |
| Glu 98 - Lys 330 | |
| IgG2A | |
| Unconjugated | |
| Tag Free | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |
| 26.4 kDa | |
| Mouse IgG2a Fc, Tag Free (IGA-M5207) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # CAC20702). | |
| -20°C | |
| IgG2a Fc | |
| Mouse | |
| 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5 | |
| HEK293 | |
| Other Recombinant Proteins |