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ACROBiosystems Mouse IL-13 R alpha 1 Protein, His Tag

Marque:  ACROBiosystems IL1-M52H7-100UG

Informations supplémentaires : Poids : 0.00001kg

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Code produit. 15877027

  • 252.20€ / 100µg
Date d’expédition estimée: 03-01-2022

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Description

Description

Interleukin 13 receptor, alpha 1 is also known as IL13RA1, NR4 and CD213A1 (cluster of differentiation 213A1), The IL13 Rα1 cDNA encodes a 427 amino acid (aa) residue precursor protein with a putative 21 aa residue signal peptide, a 324 aa residue extracellular domain, a 23 aa residue transmembrane region and a 59 aa residue cytoplasmic tail. Human and mouseIL13Rα1 share 76% aa sequence identity. IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.9 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spécification

Spécification

NP_598751
HEK293
Mouse
37.9 kDa
100 µg
Ala 26 - Thr 340
IL13RA1,CD213A1,IL-13 Ra,NR4,RP13-128O4.2,IL13Rα1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Mouse IL-13 R alpha 1, His Tag (IL1-M52H7) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Thr 340 (Accession # NP_598751).
-20°C
IL-13 R alpha 1
His Tag
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