missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Mouse IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free

Marque:  ACROBiosystems ILB-M52W7-50UG

Informations supplémentaires : Poids : 0.00001kg

 Afficher plus de versions de ce produit

Code produit. 15867097

  • 353.08€ / 50µg
Date d’expédition estimée: 29-12-2021

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

Mouse IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free, produced by co-expression of IL-23A and IL-12B, has a calculated MW of 20.5 kDa (IL-23A) and 35.8 kDa (IL-12B). Subunit IL-23A is fused with a polyhistidine tag at the N-terminus and subunit IL-12
Spécification

Spécification

NP_112542.1 (IL23A) and NP_032378.1 (IL12B)
HEK293
Mouse
20.5 kDa (IL23A) and 35.8 kDa (IL12B)
50 µg
Val 22 - Ala 196 (IL23A) and Met 23 - Ser 335 (IL12B)
IL-23 alpha and IL-12 beta
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Cytokines and Growth Factors
Powder
>90% as determined by SDS-PAGE
Mouse IL-23 A&IL-12; B Heterodimer Protein, His Tag&Tag; Free (ILB-M52W7) is expressed from human 293 cells (HEK293). It contains AA Val 22 - Ala 196 (IL23A) and Met 23 - Ser 335 (IL12B) (Accession # Q9EQ14-1 (IL23A) and P43432-1 (IL12B)).
-20°C
IL23A and IL12B
His Tag
Vidéos
FDS
Documents
Certificats
Promotions

Promotions