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ACROBiosystems Mouse IL-23 alpha&IL-12 beta Heterodimer Protein, His Tag&Tag Free
423.38€ - 4705.56€
Spécification
| Numéro d’adhésion | NP_112542.1 (IL23A) and NP_032378.1 (IL12B) |
|---|---|
| Poids moléculaire | 20.5 kDa (IL23A) and 35.8 kDa (IL12B) |
| Source | Mouse IL-23 A&IL-12; B Heterodimer Protein, His Tag&Tag; Free (ILB-M52W7) is expressed from human 293 cells (HEK293). It contains AA Val 22 - Ala 196 (IL23A) and Met 23 - Ser 335 (IL12B) (Accession # Q9EQ14-1 (IL23A) and P43432-1 (IL12B)). |
| Immunogène | Val 22 - Ala 196 (IL23A) and Met 23 - Ser 335 (IL12B) |
| Conditions de stockage | -20°C |
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
|---|---|---|---|---|---|---|---|---|---|
| Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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15867097
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ACROBiosystems
ILB-M52W7-50UG |
50 μg |
423.38€
50µg |
Expédition estimée: 30-04-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
|
15857097
|
ACROBiosystems
ILB-M52W7-1MG |
1 mg |
4705.56€
1mg |
Expédition estimée: 30-04-2024 Connectez-vous pour voir le stock disponible |
Veuillez vous connecter pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant! | ||||
Description
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Mouse IL-23A&IL-12B Heterodimer Protein, His Tag&Tag Free, produced by co-expression of IL-23A and IL-12B, has a calculated MW of 20.5 kDa (IL-23A) and 35.8 kDa (IL-12B). Subunit IL-23A is fused with a polyhistidine tag at the N-terminus and subunit IL-12Spécification
| NP_112542.1 (IL23A) and NP_032378.1 (IL12B) | |
| Mouse IL-23 A&IL-12; B Heterodimer Protein, His Tag&Tag; Free (ILB-M52W7) is expressed from human 293 cells (HEK293). It contains AA Val 22 - Ala 196 (IL23A) and Met 23 - Ser 335 (IL12B) (Accession # Q9EQ14-1 (IL23A) and P43432-1 (IL12B)). | |
| -20°C | |
| IL23A and IL12B | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| Cytokines and Growth Factors |
| 20.5 kDa (IL23A) and 35.8 kDa (IL12B) | |
| Val 22 - Ala 196 (IL23A) and Met 23 - Ser 335 (IL12B) | |
| IL-23 alpha and IL-12 beta | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |