missing translation for 'onlineSavingsMsg'
Learn More

ACROBiosystems Mouse IL-23 R Protein, Fc Tag

Marque:  ACROBiosystems ILR-M5251-100UG

Informations supplémentaires : Poids : 0.00001kg

 Afficher plus de versions de ce produit

Code produit. 15877127

  • 292.55€ / 100µg
Date d’expédition estimée: 03-01-2022

Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!


Description

Description

Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 66.8 kDa. As a result of glycosylation, the protein migrates as 90-100 kDa under reducing (R) condition, and 180-200 kDa under non-reducing (NR) condition (SDS-
Spécification

Spécification

NP_653131
HEK293
Mouse
66.8 kDa
100 µg
Gly 24 - Asp 372
IL-23 R,IL-23 Receptor
Unconjugated
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>95% as determined by SDS-PAGE
Mouse IL-23 R, Fc Tag (ILR-M5251) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Asp 372 (Accession # NP_653131).
-20°C
IL-23 R
Fc Tag
Vidéos
FDS
Documents
Certificats
Promotions

Promotions