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MRPS12 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 15225-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16804324

  • 329.85€ / 150µL

Expédition estimée
02-03-2021

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Description

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal domit deafness gene (DFNA4). Splice variants that differ in the 5′ UTR have been found for this gene; all three variants encode the same protein.
Spécification

Spécification

MRPS12
0.24 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O15235, O35680
MPR S12, MRP S12, MRPS12, MT RPS12, RPMS12, RPS12, RPSM12, S12mt
Rabbit
IgG
150 μL
-20°C
Primary
24030, 292758, 6183
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
MRPS12
Liquid
MRPS12
MRPS12 Fusion Protein Ag7442
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Vidéos
FDS
Documents