missing translation for 'onlineSavingsMsg'
Learn More

Myh9 Rabbit anti-Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

112.71€ - 329.85€

Spécification

Antigène Myh9
Concentration 0.6 mg/mL
Applications ELISA
Conjugué Unconjugated
Format Liquid
Consulter d'autres spécifications

Produits 2
Code produit Marque Quantité Prix Quantité et disponibilité  
Code produit Marque Quantité Prix Quantité et disponibilité  
16896325
Afficher les documents
Proteintech
51053-1-IG-150UL
150 μL
329.85€
150µL
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée
26-04-2021
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
16806335
Afficher les documents
Proteintech
51053-1-IG-20UL
20 μL
112.71€
20µL
Voir les produits de remplacement
Économisez jusqu'à 
»
Expédition estimée
26-04-2021
Veuillez vous pour pouvoir commander cet article. Besoin d'un compte web? Créer le vôtre dès maintenant!
Description

Description

TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport. More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein. The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1. Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer′s disease. Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex. Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.
Spécification

Spécification

Myh9
ELISA
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.6 mg/mL
Unconjugated
Rabbit
Mouse
IgG
Protein A
Antibody
FDS