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NCX1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 55075-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
Ca2+ plays a critical role in intracellular signaling and thus regulation of calcium balance is critical for the maintece of this signaling function. The plasma membrane Na+/Ca2+ (NaCX) exchangers mediate Na+-dependent Ca2+ efflux in a wide variety of cell types. NaCX can move Ca2+ either into or out of cells, depending on the net Na+, Ca2+, and K+ gradient across the membrane. In mammals, at least 5 distinct genes code for the exchangers: Three NaCX (NaCX-1, NaCX-2, and NaCX-3), and two in the NaCKX family (NaCKX-1 and NaCKX-2). NaCX-1 is most prominently expressed in the heart where it plays a major role in excitation-contraction coupling (Matsuoka et al., 1993). NACX-1 may also be a target for protection of the heart and brain from ischemia and reperfusion injury (Hagihara et al., 2005; Bano et al., 2005; Choi, 2005).Spécification
NCX1 | |
0.3 mg/mL | |
0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P32418, P70414, Q01728 | |
NCX, NCX1, SLC8A1, Sodium/calcium exchanger 1 | |
Rabbit | |
IgG | |
150 μL | |
-20°C | |
Primary | |
20541, 29715, 6546 |
Immunoprecipitation, Western Blot | |
Unconjugated | |
SLC8A1 | |
Liquid | |
SLC8A1 | |
Peptide | |
Antigen Affinity Chromatography | |
RUO | |
Antibody | |
Polyclonal | |
Human, Mouse, Rat |