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PDGFRB Monoclonal Antibody (18A2), PE, Invitrogen™

Mouse Monoclonal Antibody

Marque:  Invitrogen MA110102

Code produit. 12392123

  • 376.00€ / 100 pièces

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Description

Description

PDGFRB is a receptor tyrosine kinase and has been implicated in atherogenesis and in cell transformation by the SIS oncogene. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses PDGFRB (CD140b) to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
TRUSTED_SUSTAINABILITY
Spécification

Spécification

PDGFRB
Monoclonal
PE
Pdgfrb
AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide
Mouse
Size-exclusion chromatography
RUO
5159
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
18A2
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
P09619
Pdgfrb
CD140b-transfected NIH 3T3 cells
100 Tests
Primary
Human
Antibody
IgG1
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