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PIG3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14828-1-AP-20UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16803684

  • 140.00€ / 20µL
Expédition estimée: 12-04-2024
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Description

Description

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.
Spécification

Spécification

PIG3
Polyclonal
Unconjugated
TP53I3
p53 induced gene 3 protein, PIG3, Quinone oxidoreductase PIG3, TP53I3
Rabbit
Antigen Affinity Chromatography
RUO
9540
-20°C
Liquid
Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence
0.45 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q53FA7
TP53I3
PIG3 Fusion Protein Ag6618
20 μL
Primary
Human
Antibody
IgG
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