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PIWIL2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 14209-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16802744

  • 399.00€ / 150µL
Expédition estimée: 15-04-2024
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Description

Description

The piwi gene of Drosophila belongs to a novel class of evolutionarily conserved genes (the piwi or Argonaute family). The Piwi family is required for germ-and stem-cell development in invertebrates, and two Piwi members, MIWI and MILI (Miwi like, Piwil2, Piwi-like protein 2), are essential for spermatogenesis in mouse. MIWI and MILI partner with Piwi-interacting RNAs (piRNAs) which are 26-31 nucleotides (nt) in length; clearly distinct from the 21-23 nt of microRNAs (miRNAs) or short interfering RNAs (siRNAs). A search for murine small RNAs that might program Piwi proteins for transposon suppression revealed developmentally regulated piRNA loci, some of which resemble transposon master control loci of Drosophila. MILI might be programmed by distinct piRNA populations at different stages of germ cell development, suggesting MILI plays an important role in meiotic prophase progression.
Spécification

Spécification

PIWIL2
Polyclonal
Unconjugated
PIWIL2
Cancer/testis antigen 80, CT80, HILI, mili, piwi like 2 (Drosophila), Piwi like protein 2, PIWIL1L, PIWIL2
Rabbit
Antigen Affinity Chromatography
RUO
306011, 55124, 57746
-20°C
Liquid
Immunohistochemistry (Paraffin)
0.19 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8CDG1, Q8TC59
PIWIL2
PIWIL2 Fusion Protein Ag5423
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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