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PKC iota Rabbit anti-Chicken, Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 13883-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16802294

  • 329.85€ / 150µL

Expédition estimée
03-03-2021

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Description

Description

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.
Spécification

Spécification

PKC iota
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P41743
aPKC lambda/iota, DXS1179E, PKC iota, PKCI, PRKC lambda/iota, PRKCI, Protein kinase C iota type, protein kinase C, iota
Rabbit
IgG
150 μL
-20°C
Primary
424991, 5584
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
PRKCI
Liquid
PRKCI
PKC iota Fusion Protein Ag4990
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Chicken, Human
Vidéos
FDS
Documents