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PKC iota Rabbit anti-Chicken, Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 13883-1-AP-150UL
Informations supplémentaires : Poids : 0.00010kg
Description
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.Spécification
PKC iota | |
0.3 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P41743 | |
aPKC lambda/iota, DXS1179E, PKC iota, PKCI, PRKC lambda/iota, PRKCI, Protein kinase C iota type, protein kinase C, iota | |
Rabbit | |
IgG | |
150 μL | |
-20°C | |
Primary | |
424991, 5584 |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
Unconjugated | |
PRKCI | |
Liquid | |
PRKCI | |
PKC iota Fusion Protein Ag4990 | |
Antigen Affinity Chromatography | |
RUO | |
Antibody | |
Polyclonal | |
Chicken, Human |