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PMCA2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marque:  Proteintech 19678-1-AP-150UL

Informations supplémentaires : Poids : 0.00010kg

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Code produit. 16829154

  • 325.38€ / 150µL
Expédition estimée: 06-10-2022
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Description

Description

The calcium pump of the plasma membrane, termed PMCA ATPase, pumps calcium from the cytosol to the extracellular space. This membrane-bound enzyme is related to a number of other ATPases including the SERCA ATPase and the sodium/K+ pump. There are four different genes encoding PMCA ATPase and studies have revealed 20 isoforms of the pump generated by alternate splicing of the primary gene products. mRNA distribution studies show that gene products 1 and 4 are transcribed in most tissues, however, products 2 and 3 are more tissue specific. Transcription of the splicing variants has also been found to be tissue specific. In the pancreas, where insulin secretion is calcium dependent, the beta cells only express the 4b isoform, however the alpha and gamma cells express both 4a and 4b isoforms. Studies have also shown that different splice variants have different affinities for calcium and calmodulin.
Spécification

Spécification

PMCA2
Polyclonal
Unconjugated
ATP2B2
ATP2B2, PMCA2, PMCA2a, PMCA2i
Rabbit
Antigen Affinity Chromatography
RUO
491
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q01814
ATP2B2
Peptide
150 μL
Primary
Human
Antibody
IgG
Vidéos
FDS
Documents
Certificats
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